skin topics >> question & answer imprint sitemap German
skin topics
base creams
skin diagnosis
skin protection
general topics
problem skin
special actives
question & answer
skin testing
trade fairs & trainings
KOKO - the company
Suche - Search
How does vitamin B3 act on the skin?

Vitamin B3 (niacin) occurs either as nicotinic acid or nicotinamide. As a component of the coenzymes NAD and NADP, hence dehydrogenases, it is found in non-processed food (meats, cereals) and involved in the biochemical redox reactions. The vitamin is reabsorbed as nicotinic acid in the intestinal tract. In cosmetic products, the nicotinamide (INCI: Niacinamide) is used for skin recovering purposes due to its better water-solubility1). Furthermore nicotinamide shows anti-inflammatory effects on acne vulgaris comparable with Clindamycin2,3).  The penetration into the skin is improved by liposomal dispersions.


  1. H. Lautenschläger, Vitamine in der Kosmetik, medical Beauty Forum 2011;1:14-16 and 2011;2:16-18
  2. Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK, Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris, Int J Dermatol. 1995 Jun;34(6):434-7
  3. Khodaeini E et al., Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris, Int J. Dermatol 2013;52:999-1004

Dr. Hans Lautenschläger

Please note: The contribution is based on the state of the art at the revision date.

Kindly inform us at if you have found any misprint or any other relevant mistake on this page

© Copyright Kosmetik Konzept KOKO GmbH & Co.KG, Leichlingen,
Revision: 11.09.2015